Pregabalin CAS No 148553-50-8

Pregabalin CAS 148553-50-8

Description

Pregabalin CAS No 148553-50-8

Pregabalin CAS No 148553-50-8 for sale online at Research Chemicals Lab.

Buy Pregabalin, a compound that is chemically and structurally similar to gabapentin, with antiepileptic, analgesic, and anxiolytic properties. Pregabalin has been studied for use in a variety of disorders, including as add-on and monotherapy in refractory partial seizures, diabetic neuropathy, surgical dental pain and other pain syndromes, postherpetic neuralgia, and social anxiety disorders. Also, Pregabalin is a structural analogue of gamma-aminobutyric acid (GABA) and has anxiolytic, analgesic, and antiepileptic properties. Pregabalin is structurally related to gabapentin. The exact mechanism of action of pregabalin as an antiseizure agent has not been determined. Equally important, Pregabalin does not show direct GABA-mimetic effects, but increases neuronal GABA levels as well as produces a dose-dependent increase in glutamic acid decarboxylase activity.

Pregabalin Specification

Item Specifications
Appearance Off-white to white powder
Identification The infrared absorption spectrum of the sample should concordant with that of the spectrum of working standard of product
Solubility Sparingly soluble in water
Specific optical rotation (On an anhydrous basis)(°) +10.0° to  +12.0°
Loss of drying( w/w) ≤0.5%
Sulphate ash ≤0.1%
Heavy Metals(%) ≤20ppm
Enantiomeric purity The area of the peak due to R-Pregabalin is not more than 0.5 % the area of the S-Pregabalin.
Related substances Lactam impurities ≤0.5%
Individual impurities ≤0.5%
Total impurities ≤1.0%
Assay(%) It contains not less than 98.0% and not more than 102.0% on a dried basis.

Pregabalin

Pregabalin is mainly used for the treatment of peripheral neuropathic pain and adjuvant treatment of localized partial seizures.

Packaging and Shipping of Pregabalin

25kgs/Bag or Drum or as required by the buyer. 

Pregabalin CAS 148553-50-8 Storage:

Store in a cool, ventilated place, protect from sun, heat and moisture. Storage and transportation according to general chemical regulations.

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