2-Bromo-4-nitroimidazole CAS No 65902-59-2

2-Bromo-4-nitroimidazole CAS 65902-59-2

Description

2-Bromo-4-nitroimidazole CAS No 65902-59-2

2-Bromo-4-nitroimidazole CAS No 65902-59-2 for sale online at Research Chemicals Lab.

Buy 2-Bromo-4-nitroimidazole (CAS: 65902-59-2; molecular formula: C₃H₂BrN₃O₂; molecular weight: 191.97 g/mol) is a halogenated nitroimidazole derivative widely employed as a key intermediate in the synthesis of antitubercular, antiparasitic, and antimicrobial agents. Its structural uniqueness stems from the bromine atom at the 2-position and a nitro group at the 4-position of the imidazole ring, which enhance its reactivity in nucleophilic substitution and coupling reactions.

The compound’s scalable synthesis involves dibromination of 4-nitroimidazole followed by selective debromination, achieving >98% purity and high yields (62–79%) in kilogram-scale production. This efficiency has facilitated its use in preclinical drugs like DNDI-VL-2098 (antileishmanial) and Pretomanid (antitubercular).

 Specification

Item Specification
Appearance  Yellow powder
Purity,% ≥98%
Melting point 232.0 to 236.0 °C
Boiling point 402.5±37.0 ℃

 Usage  

2-bromo-4-nitroimidazole is an organic synthesis intermediate and pharmaceutical intermediate, which can be used in laboratory research and development process and chemical pharmaceutical synthesis process.

Packaging and Shipping of 2-Bromo-4-nitroimidazole

25kgs/Bag or Drum or as required by buyer.

2-Bromo-4-nitroimidazole  Storage:

Store in a cool, ventilated place, protect from sun, heat and moisture.Storage and transportation according to general chemical regulations.

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