L-SEPIAPTERIN CAS 17094-01-8

L-SEPIAPTERIN CAS :17094-01-8

Stability: Sepiapterin is slightly hygroscopic and is very sensitive to light. It reacts with oxygen, especially in solution. Sepiapterin is less sensitive to oxygen than tetrahydrobiopterin. Dry at ,–200C , it can be stored for several years.

Storage:  the powder should be store at –200C or colder. Solutions of sepiapterin should be made with oxygen free water and frozen as soon as possible.Sepiapterin can be transported without the use of dry ice. In tightly closed dark glass vials protected from light , it is stable at ambient temperatures for several weeks. 

Uses:Sepiapterin is often used in biological experiments. Exogenously administered sepiapterin is efficiently incorporated into cells where it is reduced to tetrahydrobiopterin.Sepiapterin is an important standard for analytical work.  

Safety information: Sepiapterin is known to be safe and there are no special precautions required in handling this product.

Description

L-SEPIAPTERIN CAS 17094-01-8

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Buy L-Sepiaterin, a naturally occurring compound that plays a role in the biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for neurotransmitter synthesis and the regulation of nitric oxide production. In research applications, L-Sepiaterin is used to study the enzymatic pathways involved in BH4 synthesis and regeneration. It is particularly useful for examining the function and activity of sepiapterin reductase, the enzyme responsible for the final step in BH4 biosynthesis. Researchers are also using L-Sepiapterin in studies to understand the etiology of diseases associated with BH4 deficiencies, such as certain forms of phenylketonuria and dihydropteridine reductase deficiency. In addition, this compound is used in experiments to evaluate the impact of BH4 on endothelial function and oxidative stress.

Specification of L-SEPIAPTERIN CAS 17094-01-8

Test Item Specification  
HPLC conditions:  Column: Waters Spherisorb S5 ODS1Eluant: 10mM Na2HPO4 PH 6-methanol, (4:1) Flow rate: 1ml/minWavelength: 254nm
TLC conditions: Stationary phase: celluloseEluant: water
UV: We do not perform uv analysis but the following data has been published:UV lambda max (log epsilon , 0.1N HCl ):409 (3.79). 271 (3.87).
Purity HPLC   >98.0%TLC    one yellow spot at 366nm

Package: 1g,5g,10g,1kg..or according to requirements.

Storage: in a dry and ventilated warehouse; keep away from sunshine and moisture.

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