α-Lipoic Acid CAS No1077-28-7

α-Lipoic Acid CAS No.: 1077-28-7

Description

α-Lipoic Acid CAS No1077-28-7

α-Lipoic Acid CAS No1077-28-7 for sale online at Research Chemicals Lab.

alpha-Lipoic Acid is a metabolic antioxidant that regulates NFkappaB signal transduction and can protect against oxidative injury. The exogenous compound is reduced intracellularly by enzymes. Its reduced form is involved in radical scavenging, recycling of other antioxidants, accelerating GSH synthesis, and regulating transcription factor activity, specifically NFkappaB. It also acts as a conenzyme that is required for the activity of pyruvate dehydrogenase and glycine decarboxylase, among other enzyme complexes. Studies show that it can prevent a decrease in the renal antioxidant defense system and prevent the increase of lipid peroxidation, platinum content and plasma creatinine concentrations. In other studies, lipoic acid decreased the phagocytosis of myelin by macrophages, acting as a non-specific scavenger of reactive oxygen species (ROS).

α-Lipoic Acid Specification

Item Specification
Appearance Yellow, crystalline powder
Identification IR/ HPLC
Melting point 60~62℃
Optical Rotation -1°~ +1°
Related Substances    Max Individual Impurity ≤0.1%               Total Impurity ≤2.0%
Polymeric Lipoic Acid ≤1.0%
Residual Solvents Cyclohexane ≤0.388%
Ethyl Acetate ≤0.50%
Toluene ≤0.089%
Loss on drying ≤0.20%
Residue on Ignition ≤0.10%
Assay 99.0%~101.0%(on the dried basis)

α-Lipoic Acid Usage

Vitamin drugs, can stimulate fat metabolism.It is used for the treatment of acute and chronic hepatitis, liver cirrhosis, hepatic coma, fatty liver, diabetes and other diseases.

α-Lipoic Acid Packaging and Shipping

25KG/Bag or drum or as per buyer requirements.

α-Lipoic Acid Storage

 Keep container sealed and store in cold storage. Store in an inert gas environment. Moisture proof. Keep away from incompatible materials such as oxidants: thermal, photosensitive, moisture sensitive, gas sensitive, etc.

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