Description

4 6-Dichloro-2-methylpyrimidine CAS 1780-26-3

4 6-Dichloro-2-methylpyrimidine CAS 1780-26-3 for sale online at Research Chemicals Lab.

Buy 4,6-Dichloro-2-methylpyrimidine (CAS: 3932-19-2) is a halogenated pyrimidine derivative with a methyl substituent at the 2-position and chlorine atoms at the 4- and 6-positions. It serves as a critical intermediate in pharmaceutical synthesis, notably for the anticancer drug dasatinib . The compound is synthesized via cyclization of acetamidine hydrochloride with dimethyl malonate, followed by chlorination using phosphorus oxychloride (POCl₃). Optimized conditions yield up to 69.55% purity. Its reactivity at the 4- and 6-positions enables diverse functionalization, making it valuable in medicinal chemistry and materials science (e.g., OLEDs) .

Specification

4,6-Dichloro-2-methylpyrimidine Usage：

Used in the synthesis of pharmaceutical intermediates

4,6-Dichloro-2-methylpyrimidine Packaging and Shipping：

25KG/drum or as per buyer’s requirements

4,6-Dichloro-2-methylpyrimidine Storage:

Keep in dark place,Sealed in dry,Room Temperature.

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