2-Bromo-4-nitroimidazole CAS No 65902-59-2
2-Bromo-4-nitroimidazole CAS 65902-59-2
- Chemical Name: 3-Aminophenol
- CAS No.: 65902-59-2
- Assay: ≥980%
- Appearance: Yellow powder
Description
2-Bromo-4-nitroimidazole CAS No 65902-59-2
2-Bromo-4-nitroimidazole CAS No 65902-59-2 for sale online at Research Chemicals Lab.
Buy 2-Bromo-4-nitroimidazole (CAS: 65902-59-2; molecular formula: C₃H₂BrN₃O₂; molecular weight: 191.97 g/mol) is a halogenated nitroimidazole derivative widely employed as a key intermediate in the synthesis of antitubercular, antiparasitic, and antimicrobial agents. Its structural uniqueness stems from the bromine atom at the 2-position and a nitro group at the 4-position of the imidazole ring, which enhance its reactivity in nucleophilic substitution and coupling reactions.
The compound’s scalable synthesis involves dibromination of 4-nitroimidazole followed by selective debromination, achieving >98% purity and high yields (62–79%) in kilogram-scale production. This efficiency has facilitated its use in preclinical drugs like DNDI-VL-2098 (antileishmanial) and Pretomanid (antitubercular).
Specification
Item | Specification |
Appearance | Yellow powder |
Purity,% | ≥98% |
Melting point | 232.0 to 236.0 °C |
Boiling point | 402.5±37.0 ℃ |
Usage:
2-bromo-4-nitroimidazole is an organic synthesis intermediate and pharmaceutical intermediate, which can be used in laboratory research and development process and chemical pharmaceutical synthesis process.
Packaging and Shipping of 2-Bromo-4-nitroimidazole :
25kgs/Bag or Drum or as required by buyer.
2-Bromo-4-nitroimidazole Storage:
Store in a cool, ventilated place, protect from sun, heat and moisture.Storage and transportation according to general chemical regulations.
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