Description

Buy 3 3′-Diindolylmethane CAS 1968-05-4

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3,3′-Diindolylmethane is an anticancer agent. Also, 3,3′-Diindolylmethane (DIM) is a dimer of indole-3-carbinol generated in low pH environment. It inhibited cell growth with IC50 values of 17, 24 and 30 μM in MCF-7, T47D and Saos2 cell lines, respectively. DIM induced apoptosis in these cells without affecting the p53 pathway. In addition, In human nasopharyngeal carcinoma (NPC) cell line (5-8F NPC), treatment of DIM decreased the ability of cell migration and invasion dose-dependently. In rats, transplanted with NPC cells, DIM administration resulted in suppressing lymph node metastasis. Besides that, DIM was found to induce ERα target gene expression and the concomitant cell proliferation at low concentration (10μM) in the absence of E2.

3,3′-Diindolylmethane Specification and More Details:

3 3′-Diindolylmethane CAS 1968-05-4 Usage：

Pharmaceutical intermediates;A natural phytochemical found in cruciferous plants, an acid catalyzed reaction product, indole-3-methanol;It has the function of anti-tumor agent

3,3′-Diindolylmethane worldwide Packaging and Shipping：

25KG/drum

3,3′-Diindolylmethane Storage:

Stored in a dry and ventilated warehouse; keep away from sunshine; avoid fire; avoid moisture.

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